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🚨 BREAKING: A new drug for progressive MS could be a game-changer! 🧠 A potential remyelination drug called PIPE-791 is currently being tested for progressive MS, and the early stages are moving forward. Here’s what to know: ✅ PIPE-791 targets the LPA1 receptor, which plays a role in how myelin is repaired in the brain and spinal cord. ✅ The Phase 1b trial has finished enrolling both healthy volunteers people with progressive MS. ✅ The trial is using brain PET scans to see how well the drug rea
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HNPP is a hereditary demyelinating neuropathy. Most cases come from a 1.5 Mb deletion on chromosome 17p11.2 that removes one copy of PMP22. PMP22 is a Schwann cell protein that helps compact and stabilize peripheral myelin. With only half the normal amount, myelin becomes fragile and forms tomacula (sausage-like thickenings) with disorganized paranodes and shorter internodes. Potassium leak lowers conduction safety, so nerves block under pressures most people tolerate. That biology explains the
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🚨 Big news in MS research! 🚨 At this year’s ECTRIMS multiple sclerosis conference in Barcelona, researchers shared something incredible… Aerobic exercise may actually help repair myelin in people with MS — not just slow the damage 🤯 Here’s what they found in a 24-week study of 21 participants with MS: ➡️ 12 people did moderate to vigorous aerobic cycling for 30 minutes, 3x per week. ➡️ MRI scans showed signs of remyelination, especially in the thalamus and corpus callosum. ➡️ The more partici
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🧠 **Did you know?** Remyelination is like giving your toddler's brain a boost! 🔍 **What's Remyelination?** Think of it as fixing the insulation around the wires in your little one's brain. This "insulation" is called myelin, and it helps messages travel smoothly and quickly. 💡 **Why does it matter?** Well, when the brain's myelin gets repaired or rebuilt, it can help your child learn and develop better! It's like giving their brain superpowers for learning and growing! 👶 **How does it happen
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Myelin repair is possible. One of the most common questions I get is “How can I repair the damage to my myelin. In my optic nerves. My brain. My spinal cord.” That is why I created the Remyelination Workshop. I have six lessons in this workshop. I teach how myelin gets made in the body. Why and how myelin is damaged. What the exciting drugs in the development pipeline that have promising results in early basic science studies are. What natural products use the same molecular mechanisms as the dr
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